AP Chemistry
8.9 Henderson-Hasselbalch Equation
8.4 Acid-Base Reactions and Buffers
A student prepares an acetate buffer for an enzyme assay by mixing acetic acid, \(\text{CH}_3\text{COOH}\), and sodium acetate, \(\text{{NaCH}}_3\text{COO}\). The desired pH is \(5.06\), and the \(pK_a\) of acetic acid is \(4.76\). Assume that \(\log 2.0=0.30\).
Using \(\text{pH}=pK_a+\log\left(\dfrac{[\text{CH}_3\text{COO}^-]}{[\text{CH}_3\text{COOH}]}\right)\), what molar ratio of \(\text{CH}_3\text{COO}^-\) to \(\text{CH}_3\text{COOH}\) is required?
Using \(\text{pH}=pK_a+\log\left(\dfrac{[\text{CH}_3\text{COO}^-]}{[\text{CH}_3\text{COOH}]}\right)\), what molar ratio of \(\text{CH}_3\text{COO}^-\) to \(\text{CH}_3\text{COOH}\) is required?
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